Brief Information of the Compound and Protein
Compound Name
4-[4-(3-chloro-4-fluorophenyl)piperazin-1-yl]-2-phenylquinazoline
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PubChem ID
CID: 71453184
Canonical SMILES
Fc1ccc(cc1Cl)N1CCN(CC1)c1nc(nc2ccccc12)-c1ccccc1
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Compound Formula C24H20ClFN4
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 8220 nM
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