Brief Information of the Compound and Protein
Compound Name
N-[(3,4-dimethylphenyl)methyl]-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine
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PubChem ID
CID: 46742338
Canonical SMILES
Cc1ccc(CNc2nc(nnc2-c2ccccc2)-c2ccccn2)cc1C
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Compound Formula C23H21N5
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  3
1
EC50 = 1850 nM
   TI
   LI
   LO
   TS
2
EC50 = 2300 nM
   TI
   LI
   LO
   TS
3
EC50 = 2960 nM
   TI
   LI
   LO
   TS