Brief Information of the Compound and Protein
Compound Name
N-(3,3-dimethylbutyl)-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine
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PubChem ID
CID: 44631784
Canonical SMILES
CC(C)(C)CCNc1nc(nnc1-c1ccccc1)-c1ccccn1
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Compound Formula C20H23N5
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  3
1
EC50 = 2480 nM
   TI
   LI
   LO
   TS
2
EC50 = 2970 nM
   TI
   LI
   LO
   TS
3
EC50 = 3820 nM
   TI
   LI
   LO
   TS