Brief Information of the Compound and Protein
Compound Name
5-(4-methylpiperazin-1-yl)-6-phenyl-3-pyridin-2-yl-1,2,4-triazine
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PubChem ID
CID: 45099947
Canonical SMILES
CN1CCN(CC1)c1nc(nnc1-c1ccccc1)-c1ccccn1
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Compound Formula C19H20N6
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  3
1
EC50 = 8690 nM
   TI
   LI
   LO
   TS
2
EC50 = 10200 nM
   TI
   LI
   LO
   TS
3
EC50 = 21900 nM
   TI
   LI
   LO
   TS