Brief Information of the Compound and Protein
Compound Name
dimethyl 2-[(2-nitrophenyl)methylidene]propanedioate
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PubChem ID
CID: 277385
SID: 163453846
Canonical SMILES
COC(=O)C(=Cc1ccccc1[N+]([O-])=O)C(=O)OC
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Compound Formula C12H11NO6
Compound Structure
Protein Name
Toll-like receptor 4
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9QUK6
Gene Name
TLR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  3
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
2
IC50 = 420 nM
   TI
   LI
   LO
   TS
3
IC50 = 1540 nM
   TI
   LI
   LO
   TS