Brief Information of the Compound and Protein
Compound Name
3-[benzimidazol-2-ylidene(phenyl)methyl]-N-butyl-2-hydroxy-1H-indole-5-carboxamide
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Canonical SMILES
CCCCNC(=O)c1ccc2NC(=O)C(=C(c3nc4ccccc4[nH]3)c3ccccc3)c2c1
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Compound Formula C27H24N4O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 326 nM