Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEBI:7550
    Show/Hide
 PubChem ID
CID: 4474
SID: 14907905
Canonical SMILES
COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCN(C)Cc1ccccc1
    Show/Hide
Compound Formula C26H29N3O6
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4786.3 nM
   TI
   LI
   LO
   TS
CL000135 A2780ADR
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4786.3 nM
   TI
   LI
   LO
   TS
CL000009 LLC-PK1
 Cell Line Info 
Sus scrofa (Pig)  3
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
2
IC50 = 4540 nM
   TI
   LI
   LO
   TS
3
IC50 = 17500 nM
   TI
   LI
   LO
   TS
CL000167 NIH-3T3-G185
 Cell Line Info 
Mus musculus (Mouse)  7
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
2
IC50 = 5600 nM
   TI
   LI
   LO
   TS
3
IC50 = 6600 nM
   TI
   LI
   LO
   TS
4
IC50 = 7100 nM
   TI
   LI
   LO
   TS
5
IC50 = 11700 nM
   TI
   LI
   LO
   TS
6
IC50 = 14600 nM
   TI
   LI
   LO
   TS
7
IC50 > 25800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5128.61 nM