Brief Information of the Compound and Protein
Compound Name
3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaene
    Show/Hide
PubChem ID
CID: 108130
SID: 87328370
Canonical SMILES
COc1cc2CC(C)C(C)Cc3cc4OCOc4c(OC)c3-c2c(OC)c1OC
    Show/Hide
Compound Formula C23H28O6
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000352 HL-60/ADR Homo sapiens (Human)  3
1
IC50 = 1.248533 nM
   TI
   LI
   LO
   TS
2
IC50 = 139.835693 nM
   TI
   LI
   LO
   TS
3
IC50 = 4185.082528 nM
   TI
   LI
   LO
   TS
CL000886 HL60/MRP Homo sapiens (Human)  3
1
IC50 = 9.488851 nM
   TI
   LI
   LO
   TS
2
IC50 = 204.759408 nM
   TI
   LI
   LO
   TS
3
IC50 = 2249.856419 nM
   TI
   LI
   LO
   TS