Brief Information of the Compound and Protein
Compound Name
SCHISANTHERIN A
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PubChem ID
CID: 45484556
Canonical SMILES
COc1cc2[C@H](OC(=O)c3ccccc3)[C@@](C)(O)[C@@H](C)Cc3cc4OCOc4c(O)c3-c2c(OC)c1OC
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Compound Formula C29H30O9
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000352 HL-60/ADR Homo sapiens (Human)  3
1
IC50 = 0.765477 nM
   TI
   LI
   LO
   TS
2
IC50 = 110.994163 nM
   TI
   LI
   LO
   TS
3
IC50 = 3056.166874 nM
   TI
   LI
   LO
   TS
CL000886 HL60/MRP Homo sapiens (Human)  3
1
IC50 = 6.315185 nM
   TI
   LI
   LO
   TS
2
IC50 = 162.66386 nM
   TI
   LI
   LO
   TS
3
IC50 = 1636.207062 nM
   TI
   LI
   LO
   TS