Brief Information of the Compound and Protein
Compound Name
8-(4-fluoro-2-methylphenoxy)-2-morpholin-4-yl-1H-quinolin-4-one
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PubChem ID
CID: 16757579
SID: 26746660
Canonical SMILES
Cc1cc(F)ccc1Oc1cccc2c(O)cc(nc12)N1CCOCC1
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Compound Formula C20H19FN2O3
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CL000146 S21 Mus musculus (Mouse)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS