Brief Information of the Compound and Protein
Compound Name
4-morpholin-4-yl-2-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]-1H-pyrimidin-6-one
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PubChem ID
CID: 136041787
SID: 137281335
Canonical SMILES
FC(F)(F)c1ccc2nc(Cc3nc(cc(=O)[nH]3)N3CCOCC3)[nH]c2c1
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Compound Formula C17H16F3N5O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 961 nM
   TI
   LI
   LO
   TS
CL000146 S21 Mus musculus (Mouse)  1
1
IC50 = 386 nM
   TI
   LI
   LO
   TS