Brief Information of the Compound and Protein
Compound Name
4-morpholin-4-yl-2-[(4-pyridin-4-yl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
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PubChem ID
CID: 136176131
SID: 137280932
Canonical SMILES
O=c1cc(nc(Cc2nc3c(cccc3o2)-c2ccncc2)[nH]1)N1CCOCC1
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Compound Formula C21H19N5O3
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
CL000146 S21 Mus musculus (Mouse)  1
1
IC50 = 158 nM
   TI
   LI
   LO
   TS