Brief Information of the Compound and Protein
Compound Name
(13aS)-2,3,9,11-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
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PubChem ID
CID: 70692652
SID: 163442737
Canonical SMILES
COc1cc2C[C@@H]3N(CCc4cc(OC)c(OC)cc34)Cc2c(OC)c1
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Compound Formula C21H25NO4
Compound Structure
Protein Name
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
IC50 = 113.81 nM
   TI
   LI
   LO
   TS
2
IC50 = 188.96 nM
   TI
   LI
   LO
   TS
3
Ki = 64.12 nM
   TI
   LI
   LO
   TS
4
Ki = 106.45 nM
   TI
   LI
   LO
   TS