Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

CANAGLIFLOZIN

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PubChem ID

CID: 24812758

SID: 125299338

Canonical SMILES	Cc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O Show/Hide
Compound Formula	C24H25FO5S

Compound Structure

Protein Name

Protein Info

Sodium/glucose cotransporter 2

Protein Classification

Transporter

Electrochemical transporter

SLC superfamily of solute carriers

SLC05 family of sodium-dependent glucose transporters

Uniprot ID

P31639

Gene Name

SLC5A2

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	IC50 = 2.2 nM	TI LI LO TS
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	IC50 = 6.7 nM	TI LI LO TS

Biochemical Assays