Brief Information of the Compound and Protein
Compound Name
N-(3,4-dichlorophenyl)-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide
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PubChem ID
CID: 11632418
SID: 16735583
Canonical SMILES
CN1CCCC(CN2CCN(CC2)C(=O)Nc2ccc(Cl)c(Cl)c2)C1
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Compound Formula C18H26Cl2N4O
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 400 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
2
IC50 = 965 nM
   TI
   LI
   LO
   TS