Brief Information of the Compound and Protein
Compound Name
4-[[(3S)-1-cyclopropylpiperidin-3-yl]methyl]-N-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
    Show/Hide
PubChem ID
CID: 57656938
Canonical SMILES
FC(F)(F)c1cccc(NC(=O)N2CCN(C[C@@H]3CCCN(C3)C3CC3)CC2)c1
    Show/Hide
Compound Formula C21H29F3N4O
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
2
IC50 = 578 nM
   TI
   LI
   LO
   TS