Brief Information of the Compound and Protein
Compound Name
N-(3,4-dichlorophenyl)-4-[(2R)-4-ethylpiperazine-2-carbonyl]piperazine-1-carboxamide
    Show/Hide
PubChem ID
CID: 57656871
Canonical SMILES
CCN1CCN[C@H](C1)C(=O)N1CCN(CC1)C(=O)Nc1ccc(Cl)c(Cl)c1
    Show/Hide
Compound Formula C18H25Cl2N5O2
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
IC50 = 55 nM
   TI
   LI
   LO
   TS