Brief Information of the Compound and Protein
Compound Name
2-(1-benzothiophen-2-yl)-N-(2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide
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PubChem ID
CID: 25095480
SID: 56415076
Canonical SMILES
O=C(Nc1ccccc1N1CCNCC1)c1csc(n1)-c1cc2ccccc2s1
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Compound Formula C22H20N4OS2
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 1500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM