Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-6-[4-(pyrrolidine-1-carbonyl)phenyl]-3,4-dihydroisoquinolin-1-one
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 PubChem ID
CID: 25218401
SID: 57560064
Canonical SMILES
C[C@@H]1CCCN1CCN1CCc2cc(ccc2C1=O)-c1ccc(cc1)C(=O)N1CCCC1
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Compound Formula C27H33N3O2
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.2 nM
   TI
   LI
   LO
   TS