Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(cyclopropylmethyl)-4-[4-(2,6-dimethylpyridin-3-yl)oxyphenyl]-2-oxopyridine-3-carbonitrile
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 PubChem ID
CID: 70685767
Canonical SMILES
Cc1ccc(Oc2ccc(cc2)-c2ccn(CC3CC3)c(=O)c2C#N)c(C)n1
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Compound Formula C23H21N3O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 263 nM
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