Brief Information of the Compound and Protein
Compound Name
4-[3-chloro-4-(cyclopropylmethoxy)phenyl]-1-(3-methylbutyl)-2-oxopyridine-3-carbonitrile
    Show/Hide
PubChem ID
CID: 70685763
Canonical SMILES
CC(C)CCn1ccc(-c2ccc(OCC3CC3)c(Cl)c2)c(C#N)c1=O
    Show/Hide
Compound Formula C21H23ClN2O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS