Brief Information of the Compound and Protein
Compound Name
1-(cyclobutylmethyl)-4-[4-(2-methylpyridin-4-yl)oxyphenyl]-2-oxopyridine-3-carbonitrile
    Show/Hide
PubChem ID
CID: 70694131
Canonical SMILES
Cc1cc(Oc2ccc(cc2)-c2ccn(CC3CCC3)c(=O)c2C#N)ccn1
    Show/Hide
Compound Formula C23H21N3O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 126 nM
   TI
   LI
   LO
   TS