Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
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 PubChem ID
CID: 5002
SID: 14756073
Canonical SMILES
OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12
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Compound Formula C21H25N3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
2
Ki = 101 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 120.23 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 82 nM
2 Ki = 120 nM
3 Ki = 202 nM
4 Ki = 220 nM
5 Ki = 1000 nM