Brief Information of the Compound and Protein
Compound Name
 Compound Info 
FENOBAM
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 PubChem ID
CID: 135413554
SID: 12015575
Canonical SMILES
CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1
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Compound Formula C11H11ClN4O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 43 nM
   TI
   LI
   LO
   TS
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 36.3 nM
   TI
   LI
   LO
   TS
2
Ki = 162.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 61 nM
2 Ki = 6.761 nM