Brief Information of the Compound and Protein
Compound Name
(E)-N-[2-(4-cyclopropyl-4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl]-3-[4-(difluoromethyl)phenyl]prop-2-enamide
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PubChem ID
CID: 70691721
Canonical SMILES
Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(cc3)C(F)F)cc12)N1CCC(O)(CC1)C1CC1
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Compound Formula C27H28F2N4O2
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2500 nM
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