Brief Information of the Compound and Protein
Compound Name
N-[4-[4-(2,4-dimethoxyphenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
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PubChem ID
CID: 11634267
SID: 16737430
Canonical SMILES
COc1ccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccccn3)CC2)c(OC)c1
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Compound Formula C28H34N4O3
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
EC50 = 2840 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 2840 nM
   TI
   LI
   LO
   TS