Brief Information of the Compound and Protein
Compound Name
N-[6-[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]oxypyridin-3-yl]acetamide
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PubChem ID
CID: 57403630
Canonical SMILES
CC(=O)Nc1ccc(Oc2c(C)nn(c2C)-c2ccc(C#N)c(Cl)c2)nc1
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Compound Formula C19H16ClN5O2
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  3
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 1600 nM
   TI
   LI
   LO
   TS
3
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS