Brief Information of the Compound and Protein
Compound Name
(5R)-5-[4-chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
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PubChem ID
CID: 11592357
SID: 16694818
Canonical SMILES
COc1ccc2c(noc2c1)-n1c2ccc(cc2n(Cc2cc(ccc2Cl)[C@@]2(C)OC(O)=NC2=O)c1=O)C(F)(F)F
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Compound Formula C27H18ClF3N4O6
Compound Structure
Protein Name
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.7 nM