Brief Information of the Compound and Protein
Compound Name
6-amino-2-[(4-tert-butylphenyl)methylsulfanyl]-3-methylpyrimidin-4-one
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PubChem ID
CID: 56951318
SID: 135658179
Canonical SMILES
Cn1c(SCc2ccc(cc2)C(C)(C)C)nc(N)cc1=O
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Compound Formula C16H21N3OS
Compound Structure
Protein Name
Sodium channel protein type 9 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Voltage-gated sodium channel
Uniprot ID
Q15858
Gene Name
SCN9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
2
IC50 = 420 nM
   TI
   LI
   LO
   TS
3
IC50 = 500 nM
   TI
   LI
   LO
   TS