Brief Information of the Compound and Protein
Compound Name
(E)-1-(2-hydroxynaphthalen-1-yl)-3-(4-methoxyphenyl)prop-2-en-1-one
    Show/Hide
PubChem ID
CID: 12388142
Canonical SMILES
COc1ccc(\C=C\C(=O)c2c(O)ccc3ccccc23)cc1
    Show/Hide
Compound Formula C20H16O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000756 MCF/MX Homo sapiens (Human)  1
1
IC50 = 3810 nM
   TI
   LI
   LO
   TS
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 2890 nM
   TI
   LI
   LO
   TS