Brief Information of the Compound and Protein
Compound Name
7-(furan-3-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
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PubChem ID
CID: 49841719
SID: 104168320
Canonical SMILES
CN1CCN(CC1)c1nc(N)nc2cc(ccc12)-c1ccoc1
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Compound Formula C17H19N5O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
2
Ki = 4 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 6 nM
   TI
   LI
   LO
   TS