Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(4-cyanophenyl)-2,5-dimethyl-1-(pyridin-3-ylmethyl)pyrrole-3-carbonitrile
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 PubChem ID
CID: 10308517
SID: 15316201
Canonical SMILES
Cc1c(C#N)c(c(C)n1Cc1cccnc1)-c1ccc(cc1)C#N
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Compound Formula C20H16N4
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  6
1
EC50 = 2200 nM
   TI
   LI
   LO
   TS
2
EC50 = 3600 nM
   TI
   LI
   LO
   TS
3
EC50 > 10000 nM
   TI
   LI
   LO
   TS
4
IC50 = 65 nM
   TI
   LI
   LO
   TS
5
IC50 = 180 nM
   TI
   LI
   LO
   TS
6
IC50 = 190 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 23 nM
   TI
   LI
   LO
   TS