Brief Information of the Compound and Protein
Compound Name
(3R,4S)-4-(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-ylmethylamino)-1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]piperidin-3-ol
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PubChem ID
CID: 57395838
Canonical SMILES
COc1ccc2ncc(F)c(CCN3CC[C@H](NCc4cc5OCCOc5cn4)[C@H](O)C3)c2n1
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Compound Formula C24H28FN5O4
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7900 nM