Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-tert-butyl-2-[3-(6-fluoro-1H-benzimidazol-2-yl)phenyl]imidazo[1,2-a]pyridin-3-amine
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 PubChem ID
CID: 56925453
SID: 135607657
Canonical SMILES
CC(C)(C)Nc1c(nc2ccccn12)-c1cccc(c1)-c1nc2ccc(F)cc2[nH]1
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Compound Formula C24H22FN5
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000008 H4
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 930 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 312 nM
2 Ki = 301 nM