Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[methyl(methylsulfonyl)amino]-N-[(1S)-1-phenylethyl]-5-(5-phenyl-1H-imidazol-2-yl)benzamide
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 PubChem ID
CID: 57395865
Canonical SMILES
C[C@H](NC(=O)c1cc(cc(c1)-c1nc(c[nH]1)-c1ccccc1)N(C)S(C)(=O)=O)c1ccccc1
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Compound Formula C26H26N4O3S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000008 H4
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 450 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 315 nM
2 Ki = 304 nM