Brief Information of the Compound and Protein
Compound Name
methyl (1R,2S,3S,5R)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
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PubChem ID
CID: 70697274
Canonical SMILES
COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@@H]1c1ccc(F)cc1)N2C
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Compound Formula C16H20FNO2
Compound Structure
Protein Name
Sodium-dependent serotonin transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P31645
Gene Name
SLC6A4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000009 LLC-PK1 Sus scrofa (Pig)  1
1
Ki = 181 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 160 nM
2 IC50 = 692 nM
3 IC50 = 759 nM
4 Ki = 63 nM