Brief Information of the Compound and Protein
Compound Name
2-[3-cyano-5-(2,4-difluorophenyl)-4,5-dimethylfuran-2-ylidene]propanedinitrile
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PubChem ID
CID: 21337671
SID: 124398794
Canonical SMILES
CC1=C(C#N)C(OC1(C)c1ccc(F)cc1F)=C(C#N)C#N
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Compound Formula C16H9F2N3O
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  2
1
EC50 = 53900 nM
   TI
   LI
   LO
   TS
2
IC50 = 48900 nM
   TI
   LI
   LO
   TS