Brief Information of the Compound and Protein
Compound Name
2-[5-(4-butylphenyl)-3-cyano-4,5-dimethylfuran-2-ylidene]propanedinitrile
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PubChem ID
CID: 12138434
SID: 124398793
Canonical SMILES
CCCCc1ccc(cc1)C1(C)OC(=C(C#N)C#N)C(C#N)=C1C
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Compound Formula C20H19N3O
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  2
1
EC50 = 15300 nM
   TI
   LI
   LO
   TS
2
IC50 = 6400 nM
   TI
   LI
   LO
   TS