Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S)-3-(4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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 PubChem ID
CID: 49851364
SID: 104221130
Canonical SMILES
CC(C)([C@@H](c1ccccc1)c1ccc(O)cc1)C(=O)Nc1nccs1
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Compound Formula C20H20N2O2S
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 29.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 40.9 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 372 nM
   TI
   LI
   LO
   TS
2
EC50 = 372.1 nM
   TI
   LI
   LO
   TS
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 250.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 251 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.2 nM