Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate
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 PubChem ID
CID: 5833
SID: 22395181
Canonical SMILES
CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12
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Compound Formula C24H32O4S
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000162 HeLa S3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 1902.5 nM
   TI
   LI
   LO
   TS
2
Ki = 864.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 20000 nM
2 IC50 = 1400 nM
3 IC50 = 4100 nM
4 Ki = 32.6 nM