Brief Information of the Compound and Protein
Compound Name
4-[3-[[2-[[1-methyl-5-(trifluoromethyl)indazol-3-yl]amino]acetyl]amino]azetidin-1-yl]cyclohexane-1-carboxamide
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Canonical SMILES
Cn1nc(NCC(=O)NC2CN(C2)[C@H]2CC[C@H](CC2)C(N)=O)c2cc(ccc12)C(F)(F)F
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Compound Formula C21H27F3N6O2
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS