Brief Information of the Compound and Protein
Compound Name
(6R)-3-[(1S)-1-[4-(4-fluorophenyl)phenyl]propyl]-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one
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PubChem ID
CID: 53473138
SID: 126517985
Canonical SMILES
CC[C@H](N1CC[C@@](CCCO)(OC1=O)c1ccccc1)c1ccc(cc1)-c1ccc(F)cc1
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Compound Formula C28H30FNO3
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 18.7 nM
   TI
   LI
   LO
   TS