Brief Information of the Compound and Protein
Compound Name
2-[(6S)-3-[(1S)-1-[4-(2,4-difluorophenyl)phenyl]ethyl]-6-(4-fluorophenyl)-2-oxo-1,3-oxazinan-6-yl]acetamide
    Show/Hide
PubChem ID
CID: 53473234
SID: 126518088
Canonical SMILES
C[C@H](N1CC[C@@](CC(N)=O)(OC1=O)c1ccc(F)cc1)c1ccc(cc1)-c1ccc(F)cc1F
    Show/Hide
Compound Formula C26H23F3N2O3
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 2.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 62 nM
   TI
   LI
   LO
   TS