Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6S)-3-[(1S)-1-[4-(2,4-difluorophenyl)phenyl]ethyl]-6-(4-fluorophenyl)-6-(2-hydroxyethyl)-1,3-oxazinan-2-one
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 PubChem ID
CID: 53361128
SID: 125263280
Canonical SMILES
C[C@H](N1CC[C@@](CCO)(OC1=O)c1ccc(F)cc1)c1ccc(cc1)-c1ccc(F)cc1F
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Compound Formula C26H24F3NO3
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 0.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 17.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17.74 nM