Brief Information of the Compound and Protein
Compound Name
1-[[3,5-dimethyl-1-[[2-(trifluoromethyl)phenyl]methyl]pyrazol-4-yl]methyl-methylamino]-3-[4-(trifluoromethyl)phenoxy]propan-2-ol
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PubChem ID
CID: 51036775
SID: 117697276
Canonical SMILES
CN(CC(O)COc1ccc(cc1)C(F)(F)F)Cc1c(C)nn(Cc2ccccc2C(F)(F)F)c1C
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Compound Formula C25H27F6N3O2
Compound Structure
Protein Name
Toll-like receptor 4
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9QUK6
Gene Name
TLR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
IC50 = 27300 nM
   TI
   LI
   LO
   TS