Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-amino-5-(2-chloro-5-methylthiophen-3-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one
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 PubChem ID
CID: 56658437
Canonical SMILES
CN1C(N)=NC(C1=O)(c1cc(C)sc1Cl)c1cccc(c1)-c1cncnc1
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Compound Formula C19H16ClN5OS
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 2230 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 470 nM