Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1,1-dioxothian-4-yl)-4-(3-quinolin-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxamide
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 PubChem ID
CID: 56675800
Canonical SMILES
O=C(NC1CCS(=O)(=O)CC1)N1CCC(CC1)c1nc(no1)-c1ccc2ccccc2n1
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Compound Formula C22H25N5O4S
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
2
IC50 = 1600 nM
   TI
   LI
   LO
   TS