Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(2-chlorophenyl)-4-(3-quinolin-2-yl-1,2,4-oxadiazol-5-yl)piperazine-1-carboxamide
    Show/Hide
 PubChem ID
CID: 44629236
Canonical SMILES
Clc1ccccc1NC(=O)N1CCN(CC1)c1nc(no1)-c1ccc2ccccc2n1
    Show/Hide
Compound Formula C22H19ClN6O2
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
2
IC50 = 700 nM
   TI
   LI
   LO
   TS