Brief Information of the Compound and Protein
Compound Name
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
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PubChem ID
CID: 7058066
SID: 16893806
Canonical SMILES
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(O)=O
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Compound Formula C22H21NO2S
Compound Structure
Protein Name
Kinesin-like protein KIF11
Protein Classification
Other cytosolic protein
Uniprot ID
P52732
Gene Name
KIF11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 1720 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 140 nM
2 IC50 = 185.9 nM
3 IC50 = 284.9 nM
4 IC50 = 620 nM
5 IC50 = 1000 nM
6 IC50 = 1900 nM
7 Ki = 26 nM
8 Ki = 50 nM
9 Ki = 71.9 nM