Brief Information of the Compound and Protein
Compound Name
 Compound Info 
rac-N-(biphenyl-2-yl)-2-(biphenyl-3-yl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazine-7(1H)-carboxamide
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 PubChem ID
CID: 56680081
Canonical SMILES
O=C(Nc1ccccc1-c1ccccc1)N1CCN2C(=O)N(c3cccc(-c4ccccc4)c3)C(=O)C2C1
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Compound Formula C31H26N4O3
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CL000426 Shh Light II
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS